Kungani Sikhetha i-PDO ne-PGCL Ekusetshenzisweni Kobuhle
Ezweni elihlala livela lezokwelapha zobuhle, i-PDO (Polydioxanone) ne-PGCL (Polyglycolic Acid) kuvele njengezinketho ezidumile zezinqubo zobuhle ezingahlinzeki. Lezi zinto ezisebenza nge-biocompatible ziya ngokuya zithandwa ngenxa yokusebenza kahle nokuphepha kwazo, okuzenza zibe yisisekelo semikhuba yesimanje yezimonyo.
Imicu ye-PDO isetshenziswa ngokuyinhloko ezinqubweni zokuphakamisa intambo, lapho ihlinzeka ngomphumela osheshayo wokuphakamisa kuyilapho ivuselela ukukhiqizwa kwe-collagen ngokuhamba kwesikhathi. Lesi senzo esikabili asigcini nje ngokuthuthukisa ukubukeka kwesikhumba kodwa futhi sikhuthaza ukuvuselelwa kwesikhathi eside. Imicu incibilika ngokwemvelo phakathi nezinyanga eziyisithupha, ishiya ngemuva ibala eliqinile nelincane kakhulu ngaphandle kwesidingo sokuhlinzwa okuhlaselayo.
Ngakolunye uhlangothi, i-PGCL ivame ukusetshenziswa kuma-dermal fillers kanye nokwelashwa kokuvuselela isikhumba. Izakhiwo zayo eziyingqayizivele zivumela ukuhlanganiswa okubushelelezi nemvelo esikhumbeni, ukuhlinzeka ngevolumu kanye ne-hydration. I-PGCL yaziwa ngekhono layo lokuvuselela i-collagen synthesis, esiza ukuthuthukisa ukunwebeka kwesikhumba nokuthungwa. Lokhu kukwenza kube ukukhetha okuhle kakhulu kulabo abafuna ukuzuza ukubukeka okucebile nobusha ngaphandle kokuphumula okuhambisana nezinqubo zezimonyo zendabuko.
Esinye sezizathu eziyinhloko odokotela bakhetha i-PDO ne-PGCL iphrofayili yabo yokuphepha. Zombili izinto ezisetshenziswayo zigunyazwe yi-FDA futhi zinomlando omude wokusetshenziswa ezinhlelweni zezokwelapha, okuqinisekisa ukuthi iziguli zingathemba ukusebenza kahle nokuphepha kwazo. Ukwengeza, imvelo ehlasela kancane yokwelashwa okubandakanya i-PDO ne-PGCL isho ukuthi iziguli zingajabulela imiphumela ebalulekile ngesikhathi esincane sokululama.
Sengiphetha, i-PDO kanye ne-PGCL benza izinguquko embonini yobuhle ngokunikeza izinketho eziphumelelayo, eziphephile, nezingezona ezihlaselayo zokuvuselela isikhumba nokuthuthukisa. Ikhono labo lokuhlinzeka ngemiphumela esheshayo kuyilapho bekhuthaza impilo yesikhumba yesikhathi eside libenza babe ukukhetha okuthandwayo kubo bobabili odokotela namaklayenti afuna ukuzuza ukubukeka kobusha nokukhazimulayo.
